Constantine Tam, MBBS (Hons), MD, FRACP, FRCPA, The Peter MacCallum Cancer Centre, Melbourne, Australia, shares some of his highlights from ASH 2020. In particular, Prof. Tam discusses encouraging updated results from the CAPTIVATE chronic lymphocytic leukemia (CLL) trial (NCT02910583) of ibrutinib plus venetoclax. This trial found that patients who achieve confirmed measurable residual disease (MRD) negativity after 12 months can discontinue treatment and expect a durable progression-free survival. Additionally, evidence of feasibility of chimeric antigen receptor (CAR) T-cell therapy in mantle cell lymphoma was a promising finding featured at ASH 2020. This interview took place during the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, 2020.