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ASH 2025 | Key multiple myeloma breakthroughs at ASH 2025

In this interview, Mohamad Mohty, MD, PhD, Saint-Antoine Hospital, Paris, France, provides insight into some of the key multiple myeloma (MM) breakthroughs at the ASH 2025 meeting, highlighting the promising early results with in vivo CAR T-cells and mentioning the Phase III MajesTEC-3 trial (NCT05083169), which may lead to the use of anti-BCMA bispecific antibodies in earlier lines of therapy. Prof. Mohty also touches on the importance of measurable residual disease (MRD) assessment, combination therapies, quality-of-life studies, and novel innovations. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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