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COMy 2024 | Activating the immune system with CELMoDs to treat multiple myeloma

Charlotte Pawlyn, BA, MBBChir, MRCP, PhD, FRCPath, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, UK, discusses novel immune-activating agents for treating myeloma. Cereblon E3 ligase modulators (CELMoDs) enhance T-cell activity, even in cells that have been exhausted from previous T-cell engager therapies, and boost NK-cell efficacy against myeloma cells. This interview took place at The 10th World Congress on Controversies in Multiple Myeloma (COMy) in Paris, France.

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