Charlotte Pawlyn, BA, MBBChir, MRCP, PhD, FRCPath, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, UK, discusses novel immune-activating agents for treating myeloma. Cereblon E3 ligase modulators (CELMoDs) enhance T-cell activity, even in cells that have been exhausted from previous T-cell engager therapies, and boost NK-cell efficacy against myeloma cells. This interview took place at The 10th World Congress on Controversies in Multiple Myeloma (COMy) in Paris, France.
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