EBMT 2024 | Immune-mediated bone marrow failure diseases & their pathophysiology: aplastic anemia, LR-MDS & PNH
Carlo Dufour, MD, G.Gaslini Research Children’s Hospital, Genoa, Italy, gives an overview of the biology and understanding of various immune-mediated bone marrow failure diseases, including acquired aplastic anemia, low-risk myelodysplastic syndromes (LR-MDS), and paroxysmal nocturnal hemoglobinuria (PNH). Dr Dufour explains the underlying biology of these diseases, which involves immune-mediated attack of the hematopoietic stem cells, and further highlights the role of immunosuppressive therapies in treating these conditions. This interview took place at the 50th Annual Meeting of the EBMT in Glasgow, Scotland.
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