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ASCO 2023 | The potential of CAR-T therapy targeting mutant CALR in myelofibrosis & essential thrombocythemia

Ciro Rinaldi, MD, PhD, Lincoln County Hospital, Lincoln, UK, discusses the potential of CAR-T therapy targeting mutant calreticulin (CALR) in patients with myeloproliferative neoplasms (MPNs) such as myelofibrosis (MF) and essential thrombocythemia (ET). Prof. Rinaldi comments on his concern for potential side effects but highlights the curative potential of this therapy, especially for MF. This interview took place at the American Society of Clinical Oncology (ASCO) 2023 Annual Congress in Chicago, IL.

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