Jean-Jacques Kiladjian, MD, PhD, Saint-Louis Hospital & Paris Diderot University, Paris, France, comments on the findings of a study investigating the characteristics and outcomes of a large cohort of young patients with myeloproliferative neoplasms (MPNs) diagnosed before 25 years of age. The study found that most young patients were females with essential thrombocythemia (ET). In addition, the study showed that while the molecular landscape of young patients was similar to that of older patients, young patients had a high incidence of complications and hematologic transformation, highlighting the need for better disease management in young patients with MPNs. This interview took place virtually.