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CAR-T Meeting 2025 | Working towards the harmonization of CAR-T registries

In this video, Ulrich Jäger, MD, Medical University of Vienna, Vienna, Austria, briefly comments on the importance of harmonizing CAR-T registries. He highlights that consortia, such as T2EVOLVE and GoCART, and large study groups are working on standardizing parameters for these registries to enable comparison across them. This harmonization will also be expanded to translational issues. This interview took place at the EHA-EBMT 7th European CAR T-cell Meeting, held in Strasbourg, France.

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Transcript (AI-generated)

As we move forward in this expanding field, I think it’s increasingly important that the people who run registries, for instance, or who do studies, translational basic studies, clinical studies, get together and find the same language. So one of the things that we are trying to harmonize within T2Evolve and GoCART and with the big study groups EBMT, EHA, is that we are trying to harmonize the parameters that are put into the major registries...

As we move forward in this expanding field, I think it’s increasingly important that the people who run registries, for instance, or who do studies, translational basic studies, clinical studies, get together and find the same language. So one of the things that we are trying to harmonize within T2Evolve and GoCART and with the big study groups EBMT, EHA, is that we are trying to harmonize the parameters that are put into the major registries. So we are creating a white paper on what are the necessary parameters, how should they be called, when should for instance monitoring be applied, at which time points, and then we have a building block, so to speak, where we can compare registries for instance to each other. And that harmonizing action will also be expanded to translational issues in a second block, let’s say so that they’re nice to have things.

 

This transcript is AI-generated. While we strive for accuracy, please verify this copy with the video.

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