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IMS 2021 | MagnetisMM-3: elranatamab for myeloma

Alexander Lesokhin, MD, Memorial Sloan-Kettering Cancer Center, New York, NY, discusses the MagnetisMM-3 trial (NCT04649359), a study investigating whether single-agent elranatamab (PF-06863135) can provide clinical benefit in patients with relapsed/refractory multiple myeloma. Elranatamab is a bispecific antibody that binds to two antigens, CD3 on T-cells and B-cell maturation antigen (BCMA). By bringing T-cells and cancer cells in close proximity, elranatamab can activate the T-cell killing of myeloma cells. This interview took place during the 2nd Immune Effector Cell Therapy in MM Workshop in Boston, MA.