In this video, Saad Kenderian, MB, CHB, Mayo Clinic, Rochester, MN, discusses the challenges associated with using CAR-T cell therapy in clinical practice, including effectively managing toxicities, overcoming resistance, and improving access to these agents. Dr Kenderian also shares some insights into strategies that may be used to overcome these challenges, and further explains how the tumor microenvironment plays a role in resistance to CAR-T therapy. This interview took place at the Tenth Annual Meeting of the Society of Hematologic Oncology (SOHO) held in Houston, TX.
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