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Relapse after HSCT 2021 | Improving virus-specific T-cell therapy

Susan Prockop, MD, Memorial Sloan Kettering Cancer Center, New York, NY, discusses strategies aiming to improve the efficacy of viral-specific T-cells (VSTs). Research is currently being conducted to increase the immunogenicity of Epstein-Barr virus (EBV)-associated tumors by inducing expression of immunogenic proteins that VSTs can target. In addition, Dr Prockop describes how it is important to better understand the interaction between adoptively transferred T-cells and the recipient immune system to improve response durability. This interview took place at the 2021 Relapse After HSCT² Workshop in New York, NY.