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IMS 2026 | Ramantamig safety and efficacy in relapsed/refractory multiple myeloma

Jeffrey Matous, MD, discusses updated safety and efficacy data for ramantamig, a dual-targeting BCMA- and GPRC5D-directed T-cell-redirecting antibody, from the Phase I TRIlogy-1 trial (NCT05652335) in patients with relapsed/refractory (R/R) multiple myeloma. He highlights the absence of new safety signals and suggests that treatment-related adverse effects, including taste disturbances associated with GPRC5D targeting, may be less frequent than with earlier agents targeting these antigens. This interview took place at the 23rd International Myeloma Society (IMS) Annual Meeting in Glasgow, UK.

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