In this interview, Torsten Haferlach, MD, of MLL Munich Leukemia Laboratory, Munich, Germany, comments on the benefits of the use of measurable residual disease (MRD) to inform treatment decisions rather than having to rely on morphology assessments. This video was recorded at the 2018 European School of Hematology (ESH) Clinical Updates on Acute Leukemias, held in Budapest, Hungary.