Paul Richardson, MD, Dana-Farber Cancer Institute, Boston, MA, addresses the challenge of bridging therapy to CAR-T in multiple myeloma (MM). Given the resistance often encountered in this heavily pretreated population, Dr Richardson underscores the need for innovative approaches to disease control with minimal toxicity. He highlights several novel agents, including cereblon E3 ligase modulators (CELMoDs), selinexor, and melflufen-based bridging therapies. This interview took place at The 10th World Congress on Controversies in Multiple Myeloma (COMy) in Paris, France.
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