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ASH 2023 | Real-world analysis of the MOST study: factors impacting progression to MF in patients with ET

In this video, Ruben Mesa, MD, Levine Cancer Institute, Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston Salem, NC, discusses a real-world analysis of the MOST study (NCT02953704), which is evaluating disease progression to myelofibrosis (MF) in patients with essential thrombocythemia (ET). Dr Mesa gives an overview of factors contributing to disease progression, including time and white blood cell (WBC) count at baseline, and further comments on the limitations of this study. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Research Funding: Promedior, Incyte, Genetech, Abbvie, Samus, Celgene, Constellation, CTI BioPharma., a Sobi Company, Mays Cancer Center, NCI; Consultancy: Constellation,  LaJolla Pharma, Sierra Onc, Novartis.