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ASH 2024 | Results of the UK Myeloma Research Alliance (UK-MRA) Myeloma XIV FiTNEss trial

In this interview, Charlotte Pawlyn, BA, MBBChir, MRCP, PhD, FRCPath, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, UK, shares findings from the UK-MRA FiTNEss trial (NCT03720041), a study that aimed to investigate the use of frailty-adapted therapy in older transplant-ineligible patients with multiple myeloma. While the primary endpoint of early treatment cessation within 60 days did not show a significant difference between the two arms, the study found evidence of improved event-free survival (EFS) and overall survival (OS) in patients receiving frailty-adjusted therapy. This interview took place at the 66th ASH Annual Meeting and Exposition, held in San Diego, CA.

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