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ASH 2018 | A step towards next-generation immune monitoring in multiple myeloma?

Improved understanding of the tumor immune microenvironment (TIME) and its influence on response to therapy is needed. Here, Bruno Paiva, PhD, of the University of Navarra, Pamplona, Spain, discusses the phenotypic, molecular and functional profiling of granulocytic myeloid-derived suppressor cells (G-MDSCs) in the TIME of multiple myeloma (MM). This revealed three unique subsets of G-MDSCs and a number of optimal markers for monitoring them, with important potential implications. This interview took place at the American Society of Hematology (ASH) 2018 Annual Meeting and Exposition in San Diego, CA.

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