Carsten Niemann, MD, PhD, Copenhagen University Hospital, Copenhagen, Denmark, highlights the need for find the optimal duration of treatment in patients with chronic lymphocytic leukemia (CLL). Personalized treatments with durations based on patient needs, existing comorbidities, or disease factors can change how quickly patients can respond to treatment. Minimal residual disease (MRD) testing is therefore, important for personalized medicine by assessing when individual patients should cease treatment. This interview took place at the 63rd ASH Annual Meeting and Exposition congress in Atlanta, GA.