Farrukh Awan, MD, UT Southwestern Medical Center, Dallas, TX, gives an update on the Phase I/II study BELLWAVE-001 (NCT03162536) evaluating the non-covalent BTK inhibitor nemtabrutinib in patients with chronic lymphocytic leukemia (CLL) who have progressed following a BTK inhibitor or/and a BCL-2 inhibitor. The study reported encouraging response rates with a limited incidence of grade ≥ 3 adverse events. This interview took place at the 28th Congress of the European Hematology Association (EHA) 2023 in Frankfurt, Germany.
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