Copanlisib for relapsed/refractory NHL: results of the CHRONOS-1 study

George Follows

Copanlisib is a novel PI3K inhibitor, targeting both PI3K-α and PI3K-δ isoforms in malignant B-cells. It was granted FDA approval based on data from the Phase II CHRONOS-1 study (NCT01660451) investigating copanlisib in relapsed/refractory B-cell non-Hodgkin lymphoma (NHL). Here, George Follows, BMBCh, PhD, FRCP, FRCPath, of Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK, discusses the longer term follow-up data being presented at the American Society of Hematology (ASH) 2017 Annual Meeting and Exposition in Atlanta, GA.

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