Daniel DeAngelo, MD, PhD, Dana-Farber Cancer Institute, Boston, MA, shares his thoughts on the importance of diagnostic pathology in hematological malignancies. Having a definitive diagnosis based on a pathology review at an academic center is crucial to guide the most appropriate treatment course, and to ultimately get the best outcomes. This interview took place during the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, 2020.