John Kuruvilla, MD, FRCPC, Princess Margaret Cancer Centre, Toronto, ON, Canada, speaking at the 17th International Workshop on Non-Hodgkin Lymphoma, Boston, MA, discusses the use of pembrolizumab in the treatment of varying lymphomas. Dr Kuruvilla discusses the parallels between Hodgkin lymphoma and primary mediastinal lymphoma, and suggests an increase in usage of the drug as treatment for Richter transformation, CNS disease, and testicular involvement.