Artur Jurczyszyn, MD, PhD, Jagiellonian University Medical College, Kraków, Poland, discusses recent data in the AL amyloidosis space that has the potential to change the standard of care. The Phase III ANDROMEDA study (NCT03201965) evaluated daratumumab in combination with cyclophosphamide, bortezomib, and dexamethasone (CyBorD), compared to CyBorD. Significant benefit was elicited with the additional use of daratumumab, leading to daratumumab becoming the first drug to be approved for the treatment of AL amyloidosis. The daratumumab plus CyBorD combination is emerging as a new standard of care. This interview took place during the 7th World Congress on Controversies in Multiple Myeloma (COMy), 2021.