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SOHO 2025 | First-in-human Phase I study of JNJ-5322, a novel trispecific antibody, in R/R myeloma

Hans Lee, MD, Sarah Cannon Research Institute, Nashville, TN, shares promising results from the first-in-human Phase I study of JNJ-5322 (JNJ-79635322), a novel trispecific antibody, in patients with triple-class-exposed relapsed/refractory (R/R) multiple myeloma. Dr Lee highlights the encouraging safety profile and efficacy of this agent, noting that this may reflect a paradigm shift in the treatment of multiple myeloma. This interview took place at the 13th Annual Meeting of the Society of Hematologic Oncology (SOHO 2025) in Houston, TX.

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