Christopher Hourigan, DM, DPhil, FACP, FRCP, of the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, discusses his group’s work on the impact of conditioning intensity of allogeneic transplantation for acute myeloid leukemia (AML) with genomic evidence of residual disease. This interview took place at the 24th Congress of the European Hematology Association (EHA) 2019, held in Amsterdam, Netherlands.