Suzanne Trudel, MSc, MD, University of Toronto Princess Margaret Cancer Centre, Toronto, Canada, discusses the findings of a study that investigated the impact of renal impairment on the clinical outcomes with mezigdomide, a novel oral cereblon E3 ligase modulator (CELMoD), plus dexamethasone (dex) in patients with relapsed/refractory (R/R) multiple myeloma (MM). Renal dysfunction did not compromise the efficacy of the treatment, and the safety profile was comparable to that seen in the intend-to-treat population. This interview took place during the 2024 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.
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