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CAR-T Meeting 2024 | Components of the CAR-HEMATOTOX model which allow for prediction of ICAHT following CAR-T

Kai Rejeski, MD, Memorial Sloan Kettering Cancer Center, New York, NY, discusses the CAR-HEMATOTOX model, which aids in determining whether a patient receiving CAR T-cell therapy is at risk of developing immune effector cell-associated hematotoxicity (ICAHT). The five components of this model include absolute neutrophil count (ANC), hemoglobin levels, platelet count, and two indicators of baseline inflammation – C-reactive protein (CRP) and ferritin. This interview took place at the EBMT-EHA 6th European CAR T-cell Meeting in Valencia, Spain.

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Disclosures

Consultancy: BMS/CELGENE
Honoraria: BMS/CELGENE, Novartis
Travel Support: Kite/Gilead, Pierre-Fabre
Research Funding: Kite/Gilead