ICML 2023 | ‘Off-the-shelf’ EBV-specific CAR-T cells for Hodgkin lymphoma
Carlos Almeida Ramos, MD, PhD, Baylor College of Medicine, Houston, TX, discusses the benefits of CD30-targeting CAR-modified Epstein-Barr virus-specific T-cells (CD30.CAR EBVSTs), a type of CAR-T cell modified to only react against EBV antigens, avoiding the risk of graft-versus-host disease (GvHD). Prof. Almeida Ramos describes how this ‘off-the-shelf’ CAR-T product may allow patients with Hodgkin lymphoma (HL) to be treated quickly and may benefit patients whose own immune cells are damaged. This interview took place at the 17th International Conference on Malignant Lymphoma (ICML), held in Lugano, Switzerland.
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Disclosures
Consultant or advisory role: Novartis, Genentech, CRISPR Therapeutics
Research funding: Tessa Therapeutics, Athenex Therapeutics
Other remuneration: Royalties: Tessa Therapeutics
