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CAR-T Meeting 2023 | Improving CAR-T cell efficacy: optimizing CAR constructs and counteracting tumor escape

In this video, Sonia Guedan, PhD, IDIBAPS-Hospital Clinic Barcelona, Barcelona, Spain, briefly discusses strategies to improve CAR-T cell efficacy, highlighting the importance of optimizing CAR constructs and counteracting mechanisms of tumor escape. This interview took place at the EBMT-EHA 5th European CAR T-cell Meeting held in Rotterdam, The Netherlands.

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Disclosures

I am inventor on patents related to CAR-T cell therapy, filed by the University of Pennsylvania and licensed to Novartis and Tmunity Therapeutics. I have received commercial research funding from Gilead. I have received lecture fees from Bristol Myers-Squibb, Roche and Gilead.