ASH 2023 | Pirtobrutinib, venetoclax, and rituximab in the treatment of R/R CLL: insights from the BRUIN trial
Catherine Coombs
• 8 Dec 2023
Catherine Coombs, MD, UC Irvine Health, Orange, CA, comments on an extension of the BRUIN trial (NCT03740529), which has found promising efficacy of pirtobrutinib combined with venetoclax ± rituximab in the treatment of relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL). This has led to the development of the Phase III BRUIN CLL-322 trial (NCT04965493), comparing pirtobrutinib plus venetoclax and rituximab to venetoclax and rituximab. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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