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EBMT 2023 | The benefit of CAR-T therapy over autoSCT in 3L DLCBL & the promise of bispecifics in this setting

In this video, Marjolein van der Poel, MD, PhD, Maastricht University Medical Center, Maastricht, Netherlands, comments on the superiority of CAR-T therapy over autologous transplantation in patients with diffuse large B-cell lymphoma (DLBCL) in the third-line setting. Dr van der Poel comments on the efficacy of axicabtagene ciloleucel (axi-cel) and lisocabtagene maraleucel (liso-cel) and briefly discusses the ZUMA-7 trial (NCT03391466). Finally, she explains that encouraging data suggest that bispecific antibodies could be a promising alternative for patients who relapse after second-line therapy. This interview took place at the 49th Annual Meeting of the European Group for Blood and Marrow Transplantation (EBMT) held in Paris, France.

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Disclosures

Takeda, Kite/Gilead: Honoraria