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ASH 2022 | Phase I trial of NVG-111, a ROR1-targeting BiTE alone or with ibrutinib in R/R CLL & MCL

Parag Jasani, MBBS, MRCP, FRCPath, FRCP, University College London Hospital, London, UK, briefly summarizes preliminary data from a Phase I trial evaluating a ROR1xCD3 bispecific T-cell engager (BiTE) as monotherapy or in combination with ibrutinib in patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL; NCT04763083). This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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