Alessandro Isidori, MD, PhD, Marche Nord Hospital, Pesaro, Italy, discusses the challenges in producing efficacious immuno-oncology (I-O) products for acute myeloid leukemia (AML), emphasizing the heterogeneity and immunosuppressive microenvironment observed in this disease. Dr Isidori explains the genetics of AML, and further evaluates the issue of finding agents that selectively target AML cells while preserving healthy hematopoietic cells. This interview took place at The 4th Society of Hematologic Oncology (SOHO) Italy Annual Conference, held in Rome, Italy.
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