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ASH 2022 | DLBCL in the elderly: a real-world experience in Latin America

Jorge Castillo, MD, Dana-Farber Cancer Institute, Boston, MA, comments on data from the Grupo De Estudio Latinoamericano De Linfoproliferativos (GELL), formed to create data from the Hispanic population, which is frequently under-represented in clinical trials. Looking at treatment outcomes in 180 elderly patients with diffuse large B-cell lymphoma (DLBCL), the group observed no major differences in terms of response, progression-free survival (PFS) and overall survival (OS) based on treatment intensity. There was a higher rate of death in these patients, and disease progression and treatment toxicity were the major causes, even with lower intensity treatment regimens. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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Disclosures

AstraZeneca: Research Funding; Roche: Consultancy; TG Therapeutics: Research Funding; Pharmacyclics: Consultancy, Research Funding; Cellectar: Consultancy; Beigene: Consultancy, Research Funding; Janssen: Consultancy; Abbvie: Consultancy, Research Funding.