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ASH 2023 | Analysis of clinical outcomes & HRU in patients with AML treated with venetoclax vs other therapies

Aaron Goldberg, MD, PhD, Memorial Sloan-Kettering Cancer Center, New York, NY, discusses a real-world multi-center study investigating clinical outcomes and healthcare resource utilization (HRU) in patients with newly diagnosed acute myeloid leukemia (AML) unfit for high-intensity chemotherapy. In this study, the outcomes of patients treated with venetoclax-based regimens were compared to patients treated with non-venetoclax-based regimens. Results suggest that the outcomes of patients in the real-world setting are similar to those observed in clinical trials. Interestingly, there was a significant difference observed in HRU, as patients treated with venetoclax and azacitidine spent less time in hospital than those treated with non-venetoclax-based regimens. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Consultancy: Abbvie, Genentech, Daiichi Sankyo, Astellas Pharma
Research Funding: Abbvie, Aprea, Trillium, Prelude, AROG, Pfizer, ADC Therapeutics, Daiichi Sankyo, Aptose, Celularity
Honoraria: DAVA Oncology