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COMy 2024 | Genomic differences between smoldering and multiple myeloma
Eileen Boyle, MD, PhD, University College London, London, UK, discusses the genomic differences between smoldering multiple myeloma (SMM) and multiple myeloma (MM). SMM exhibits fewer high-risk translocations like t(4;14), while MM has more adverse mutations such as del(17p), gain(1q), and del(13q). Additionally, mutations in NRAS and KRAS are more frequent in MM and serve as markers for the transformation of SMM to MM. This interview took place at The 10th World Congress on Controversies in Multiple Myeloma (COMy) in Paris, France.
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