ASH 2023 | Favezelimab plus pembrolizumab in transplant-ineligible patients with R/R classical Hodgkin lymphoma
Nathalie Johnson, MD, PhD, Jewish General Hospital, Montreal, Canada, discusses the updated analysis of an open-label Phase I/II study (NCT03598608) investigating favezelimab in combination with pembrolizumab in transplant-ineligible patients with anti–PD-1–naïve relapsed/refractory (R/R) classical Hodgkin lymphoma (cHL). The study’s primary endpoint was safety, and the combination therapy was found to have a favorable safety profile. Common adverse events reported were manageable, such as hypothyroidism and infusion-related toxicities. The progression-free survival (PFS) data were promising compared to historical controls. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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Disclosures
Consultancy: Gilead, Abbvie, Merck, Roche
Honoraria: Merck, Roche
