Thorsten Braun, MD, PhD, Hôpitaux de Paris, Université Paris 13, Bobigny, France, discusses current intensive therapy of older acute myeloid leukemia (AML) patients. Analysis of AML gene mutations can improve treatment stratification of patients who may benefit from intensive therapy and allogeneic transplantation. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).