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ASH 2023 | Optimizing HMA treatment in HR-MDS: azacitidine versus decitabine

Jan Philipp Bewersdorf, MD, Memorial Sloan Kettering Cancer Center, New York, NY, discusses the results of a retrospective analysis using the VALIDATE database, which aimed to compare the efficacy of the two currently FDA-approved hypomethylating agents (HMA), azacitidine and decitabine, in treating patients with higher-risk myelodysplastic syndromes (HR-MDS). No significant difference in overall survival (OS) was found between the two agents. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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