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ASH 2023 | Quantifying mutant MYD88 expression to track disease burden in WM

Zachary Hunter, PhD, Dana-Farber Cancer Institute, Boston, MA, presents a study utilizing allele-specific polymerase chain reaction (PCR) assays to quantify mutant MYD88 expression on CD19-selected tissue throughout the development of Waldenström’s macroglobulinemia (WM). The research demonstrates that this approach to tracking disease burden is a better predictor of progression-free survival (PFS) than standard techniques that measure serum IgM changes. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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