Dr Stein has actually presented at EHA 2023 on NK-cell engager targeting CD123, which is showing very promising data. This was a Phase I study, dose finding study, where several dosages were given. And what was very encouraging about this is, one: it is not toxic, it’s very well tolerated regimen – we always worry about, you know, cell engagers as having significant cytokine release syndrome which has marred the development of some of these agents, but this particular one, we seem to actually not have very significant cytokine release syndrome – so very well tolerated...
Dr Stein has actually presented at EHA 2023 on NK-cell engager targeting CD123, which is showing very promising data. This was a Phase I study, dose finding study, where several dosages were given. And what was very encouraging about this is, one: it is not toxic, it’s very well tolerated regimen – we always worry about, you know, cell engagers as having significant cytokine release syndrome which has marred the development of some of these agents, but this particular one, we seem to actually not have very significant cytokine release syndrome – so very well tolerated. And the second thing that’s encouraging is in one particular dose level, there was about 35% response rates in terms of complete remissions or incomplete complete remissions – CR/CRi. That’s very encouraging in a Phase I data. So obviously this is going to move forward with the additional enrollment and we’re excited to see what the what the drug does for our relapsed patients.