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ASH 2023 | suPAR and GDF-15: biomarkers indicative of endothelial injury following alloSCT

Eleni Gavriilaki • 11 Dec 2023
ASH 2023
General

Eleni Gavriilaki, MD, PhD, National and Kapodistrian University of Athens, Athens, Greece, discusses a study which determined two new biomarkers, soluble urokinase-type plasminogen activator receptor (suPAR) and growth differentiation factor-15 (GDF-15), whose levels are significantly associated with endothelial injury occuring as a result of graft-versus-host disease (GvHD) and transplant-associated thrombotic microangiopathy (TA-TMA) following allogeneic stem cell transplanatation (alloSCT). These biomarkers must now be validated in multiple cohorts. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.

Disclosures

Research Funding: Pfizer and Jazz Pharmaceuticals
Honoraria: Alexion, AstraZeneca, Omeros, Sanofi, Sobi

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