Paolo Caimi, MD, Cleveland Clinic, Cleveland, discusses outcomes following the substitution of tocilizumab with siltuximab to cope with the national tocilizumab shortage. Overall, it was observed that IL-6 blockade with siltuximab was an effective and feasible first-line therapy for cytokine release syndrome (CRS). This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.
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