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ASH 2022 | Siltuximab for first-line treatment of CRS in patients receiving CAR-T therapy
Paolo Caimi, MD, Cleveland Clinic, Cleveland, discusses outcomes following the substitution of tocilizumab with siltuximab to cope with the national tocilizumab shortage. Overall, it was observed that IL-6 blockade with siltuximab was an effective and feasible first-line therapy for cytokine release syndrome (CRS). This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.
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Disclosures
Bristol Myers Squibb: Membership on an entity’s Board of Directors or advisory committees; Genmab: Membership on an entity’s Board of Directors or advisory committees; Genentech: Membership on an entity’s Board of Directors or advisory committees; Takeda: Membership on an entity’s Board of Directors or advisory committees; MEI Pharma: Membership on an entity’s Board of Directors or advisory committees; ADC Therapeutics: Membership on an entity’s Board of Directors or advisory committees; Novartis: Membership on an entity’s Board of Directors or advisory committees; Kite Pharma: Membership on an entity’s Board of Directors or advisory committees.
