Eytan Stein, MD, Memorial Sloan Kettering Cancer Center, New York, NY, outlines the findings from a Phase II/Ib sub-study that is part of the Beat AML study group. The study investigated the efficacy of treating newly-diagnosed IDH2-mutant AML patients with enasidenib (ENA) monotherapy, a selective IDH2 inhibitor, followed by response-driven addition of azacitidine (aza). This interview took place during the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, 2020.