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Nico Gagelmann, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, discusses the impact of mutation profile in chronic myelomonocytic leukemia (CMML) undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).