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ASH 2025 | Reasons for treatment discontinuation in multiple myeloma: insights from the PREAMBLE registry

Karthik Ramasamy, MBBS, MRCP, FRCPath, PhD, Oxford University Hospitals NHS Foundation Trust, Oxford, UK, presents real-world findings from the prospective PREAMBLE study (NCT01838512) assessing rates and reasons for treatment discontinuation in patients with multiple myeloma (MM). The data indicated that discontinuation rates are high in the real-world setting, driven primarily by treatment fatigue and adverse events. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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