ASH 2022 | Risk factors for Richter’s transformation in CLL
Jennifer Woyach, MD, Ohio State University College of Medicine, Columbus, OH, briefly outlines known risk factors for Richter’s transformation in patients with chronic lymphocytic leukemia (CLL), including TP53 abnormalities, IgHV unmutated status, complex karyotype, and NOTCH1 mutations. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.
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Disclosures
Karyopharm Therapeutics: Research Funding; Schrodinger: Research Funding; Newave: Consultancy; Genentech: Consultancy; Pharmacyclics: Consultancy; ArQule: Consultancy; MorphoSys: Consultancy, Research Funding; Loxo@Lilly: Research Funding; AbbVie: Consultancy, Research Funding; Janssen: Consultancy; BeiGene: Consultancy; AstraZeneca: Consultancy.
