iwCLL 2023 | SF3B1 mutation and ATM deletion co-drive leukemogenesis through centromeric R-loop dysregulation
Lili Wang
• 7 Oct 2023
In this interview, Lili Wang, MD, PhD, City of Hope, Duarte, CA, discusses the coexpression of the SF3B1 mutation and ATM deletion and suggests that this co-occurrence controls leukemogenesis and the onset of chronic lymphocytic leukemia (CLL). Dr Wang also elucidates the mechanism by which this likely occurs, centromeric R-loop dysregulation, which she has investigated in murine cells. This interview was recorded at the biennial International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2023 meeting, held in Boston, MA.
These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.
