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iwCLL 2023 | The future of CLL treatment

In this video, Arnon Kater, MD, PhD, University of Amsterdam, Amsterdam, Netherlands, comments on the likelihood of a cure for chronic lymphocytic leukemia (CLL) and provides his opinion on the approaches to treatment of the disease which will be utilized in the following years. This interview was recorded at the biennial International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2023 meeting, held in Boston, MA.

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Transcript (edited for clarity)

I think we are not yet there for a cure, maybe we can, with the new options that we have now, including the bispecific antibodies but we of course need to prove that. But I do think that we have enough tools to really go for a smart combination, the shortest way possible, give patients a very long drug-free holiday and then reshuffle the drugs that we have and go again for a time-limited treatment, and then again for a treatment-free survival of a long time...

I think we are not yet there for a cure, maybe we can, with the new options that we have now, including the bispecific antibodies but we of course need to prove that. But I do think that we have enough tools to really go for a smart combination, the shortest way possible, give patients a very long drug-free holiday and then reshuffle the drugs that we have and go again for a time-limited treatment, and then again for a treatment-free survival of a long time. And in that way, I think it’s still not a curable disease, but then it’s really becoming a chronic disease where you have phases that you’re really good and phases that you deteriorate so you need a short period of treatment and then you’re good to go again.

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