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ASH 2022 | Opportunities and challenges for dual-targeting CAR-T therapy in ALL

Regina Myers, MD, Children’s Hospital of Philadelphia, Philadelphia, PA, discusses the use of dual-targeting CAR-T products to treat acute lymphoblastic leukemia (ALL). Whilst published data has shown that CD19/CD22 CAR-T therapy appears to be effective, it is currently difficult to achieve dual specificity for both CD19 and CD22. Dr Myers highlights a promising approach in which two independent CD22 and CD19 products were co-administered simultaneously. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

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